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Living with HRR mutations

Stories from people navigating HRR mutations — diagnosis, treatment, caregiving, and the ordinary days in between.

2 stories

Prostate cancer pathology slide beside a molecular test report and medication packaging in a clinical laboratory.

Oncology

Prostate Cancer Approval Expands Talazoparib Eligibility

The FDA has expanded talazoparib plus enzalutamide to selected adults with HRR-mutated metastatic castration-sensitive prostate cancer. Treatment requires mutation confirmation with an FDA-authorized test.

Rayan Salih · November 10, 2026 · 7 min

Prostate cancer tissue testing materials beside sealed talazoparib and enzalutamide medication packages

Oncology

Talazoparib Plus Enzalutamide for HRR-Mutated Prostate Cancer

The FDA approved talazoparib plus enzalutamide for adults with HRR-mutated metastatic prostate cancer that remains naïve or sensitive to androgen-pathway modulation. An FDA-authorized test must confirm eligibility.

Dr. Abu Bakar · 7 min read

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