Skip to content
TheBrief.Health

Diabetes, obesity and hormone health

Endocrinology & Metabolism

Metabolic medicine: glycemic management, GLP-1 therapeutics, thyroid disease and endocrine practice.

Rayan SalihRayan SalihContributing writer · PharmD, RPhDr. Abu BakarDr. Abu BakarContributing writer · PharmD, PhD (Pharmacology)Egbavwe PelaEgbavwe PelaContributing writer
Urine specimen cup beside a kidney function laboratory request and glucose meter on a clinical desk.

Endocrinology & Metabolism

Finerenone Opens Kidney Protection Path in Type 1 Diabetes

The FDA has approved finerenone for renal protection in adults with type 1 diabetes and chronic kidney disease, using albuminuria reduction as the basis for the new pathway.

Rayan Salih · November 9, 2026 · 6 min

Intravenous iron vial beside a laboratory phosphate result and infusion supplies on a clinical work surface.

Endocrinology & Metabolism

Ferric Carboxymaltose Boxed Warning Elevates Phosphate Risk

The FDA boxed warning highlights serious hypophosphatemia with ferric carboxymaltose, particularly after repeated exposure. Treatment selection should now include phosphate risk, counseling and monitoring needs.

Dr. Abu Bakar · 7 min read

A weekly medication organizer beside an insulin pen and glucose meter on a clinical desk.

Endocrinology & Metabolism

Type 2 Diabetes Gains a Once-Weekly Insulin Option

FDA approval of insulin efsitora alfa-gobe creates a weekly basal insulin option for adults with type 2 diabetes, making treatment burden, hypoglycemia risk and follow-up capacity central to selection.

Rayan Salih · 7 min read

Thyroid hormone laboratory materials beside a heart-rate cuff and pediatric growth record.

Endocrinology & Metabolism

FDA Approves First Treatment for MCT8 Deficiency

The FDA approved tiratricol as the first treatment for peripheral thyrotoxicosis in MCT8 deficiency, targeting cardiovascular and metabolic manifestations rather than the disorder’s established neurologic disability.

Dr. Abu Bakar · 6 min read

Blood pressure cuff beside adrenal imaging and laboratory request forms on a clinician’s desk.

Endocrinology & Metabolism

Primary Aldosteronism Evidence Reshapes Care Pathways

The supporting systematic review favors aldosterone-directed treatment and clearer selection between adrenalectomy and medical therapy for adults with primary aldosteronism.

Rayan Salih · 7 min read

An OTC orlistat package beside a medication list and kidney-shaped clinical model on a pharmacy counter.

Endocrinology & Metabolism

Orlistat Kidney-Injury Warning Now Covers OTC Alli

The FDA has approved revised labeling for OTC orlistat (alli) warning of rare acute kidney injury, bringing kidney-risk messaging into line across US orlistat products.

Rayan Salih · 6 min read

Insulin supplies and an infusion line arranged in a pediatric endocrinology treatment room.

Endocrinology & Metabolism

Teplizumab Expands to Pediatric Stage 3 Type 1 Diabetes

The FDA expanded teplizumab to patients ages 8–17 with stage 3 type 1 diabetes diagnosed within six weeks, based on evidence that it slows loss of insulin-producing function.

Rayan Salih · 7 min read

A positive airway pressure mask beside an injectable medication pen on a bedside table.

Endocrinology & Metabolism

FDA Approves Tirzepatide for Obstructive Sleep Apnea

Tirzepatide reduced apnea severity and body weight in adults with obesity and moderate-to-severe obstructive sleep apnea, supporting FDA approval with or without ongoing positive airway pressure therapy.

Egbavwe Pela · 7 min read

One story a day

The story of the day, in your inbox

One health journey each morning — no advice, no alarm, just company for the road.