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A Luna G3 positive airway pressure device being checked against a recall notice in a sleep clinic.

Innovation & Devices

Luna G3 APAP Recall: Identifying Patients at Risk

An FDA Class I recall covers Luna G3 APAP model LG3600 with specified firmware. Clinicians and suppliers need to identify exposed patients and protect continuity of positive airway pressure therapy.

Rayan Salih · 6 min read

An Astral ventilator beside checked backup equipment and a device inventory label in a respiratory care setting.

Innovation & Devices

Astral Ventilator Recall and Supercapacitor Failure Risk

Certain ResMed Astral 100 and 150 ventilators require correction because supercapacitor leakage may contribute to failure. Ventilator-dependent patients need prompt device checks and reliable backup plans.

Rayan Salih · 6 min read

Impella console and packaged pump sets arranged for a hospital inventory safety review.

Innovation & Devices

Impella CP Recall Demands Pump-Set Contingency Plans

A Class I recall of certain Impella CP SmartAssist sets follows persistent low-purge-pressure alarms that may interrupt support. Hospitals should identify affected inventory and plan for monitored pump exchange.

Rayan Salih · 6 min read

Breast cancer pathology slides beside a treatment-planning notebook in an oncology workspace.

Women's Health

Sacituzumab Govitecan Moves Into First-Line TNBC Care

The FDA approved first-line sacituzumab govitecan alone for patients unable to receive checkpoint inhibition and with pembrolizumab for PD-L1–positive advanced triple-negative breast cancer.

Rayan Salih · 7 min read

Stroke CT images displayed beside a hospital transfer checklist and clock

Neurology

Stroke Imaging: CT Perfusion Adds No Clear Selection Gain

Pooled evidence found no significant difference in functional independence or symptomatic intracerebral hemorrhage when CT perfusion and noncontrast CT were used to select patients for acute ischemic stroke treatment.

Dr. Abu Bakar · 6 min read

An esophageal pH capsule delivery kit beside an inventory checklist in a clinical procedure room.

Clinical Briefs

Esophageal pH Capsule Alert Signals Procedural Safety Risk

The FDA reported 184 serious injuries and no deaths involving specified Medtronic and Given Imaging esophageal pH capsule delivery devices. Gastroenterology services should review inventory, workflows and follow-up.

Rayan Salih · 7 min read

Protective equipment and clinical supplies prepared outside a high-level isolation room for filovirus care.

Infectious Disease

Ebola and Marburg Clinical Care Standards Unified by WHO

WHO has issued a unified framework for clinicians and outbreak teams managing Ebola and Marburg disease, linking supportive care with infection prevention, workforce protection, and coordinated response.

Rayan Salih · 7 min read

Lung cancer pathology slide beside immunotherapy and antibody-drug conjugate infusion bags

Oncology

Sacituzumab Tirumotecan Improves PFS in Advanced NSCLC

Interim phase 3 results favor adding sacituzumab tirumotecan to first-line pembrolizumab for PD-L1-positive advanced NSCLC, but survival, safety and generalizability remain unsettled.

Rayan Salih · 6 min read

Lung cancer tissue slide beside a molecular sequencing report highlighting an ERBB2 mutation

Oncology

Sevabertinib Approval Narrows HER2-Mutated NSCLC Use

FDA accelerated approval applies to previously treated, advanced non-squamous NSCLC with qualifying activating mutations in the HER2 tyrosine kinase domain—not every ERBB2 alteration.

Rayan Salih · 6 min read

Clinician reviewing a rabies exposure checklist beside vaccine supplies and an animal-control contact card.

Infectious Disease

Rabies Exposure Alerts Demand Prompt Clinical Action

A CDC alert describes increased reports of human rabies exposures nationwide. Clinicians need a rapid workflow for exposure assessment, public health consultation and correctly delivered prophylaxis.

Rayan Salih · 7 min read

Labeled cellular therapy bags and a cryogenic transport container in a hospital transplant laboratory.

Oncology

Treg Therapy Enters Matched-Donor Stem Cell Transplant

The FDA approved an allogeneic regulatory T-cell therapy for adults with hematologic malignancies undergoing matched-donor stem cell transplantation. Programs must assess eligibility, logistics and safety readiness.

Rayan Salih · 6 min read