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TheBrief.Health

Living with msi-h

Stories from people navigating msi-h — diagnosis, treatment, caregiving, and the ordinary days in between.

2 stories

Rectal MRI images and a pathology slide beside a multidisciplinary cancer care plan

Oncology

Dostarlimab Offers Treatment-Only Path in Rectal Cancer

Accelerated approval makes dostarlimab an initial option for previously untreated stage II or III MSI-H/dMMR rectal cancer, with the possibility of avoiding chemotherapy, radiation and surgery.

Rayan Salih · October 26, 2026 · 6 min

Pelvic MRI workstation beside a pathology slide and an oncology treatment plan for rectal cancer.

Oncology

Dostarlimab Opens Treatment-Only Path in Rectal Cancer

FDA accelerated approval covers selected previously untreated adults with MSI-H or dMMR locally advanced rectal cancer, allowing standard chemoradiation and surgery to be deferred when a complete clinical response is sustained.

Rayan Salih · 7 min read

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