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Living with treatment-resistant depression

Stories from people navigating treatment-resistant depression — diagnosis, treatment, caregiving, and the ordinary days in between.

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A quiet clinical therapy room prepared for a monitored psychiatric treatment session.

Mental & Behavioral Health

Psilocybin May Ease Treatment-Resistant Depression

Randomized evidence suggests psilocybin-assisted therapy can reduce depressive symptoms through six weeks, but safety, durability and implementation questions limit its immediate US clinical role.

Dr. Abu Bakar · October 11, 2026 · 6 min

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