Cardiology
Earlier Intervention May Improve Aortic Regurgitation Outcomes
Aortic regurgitation is a common heart valve problem where the aortic valve doesn’t close tightly.
Dr. Abu Bakar · August 9, 2026 · 6 min
Living with Valvular Heart Disease
Stories from people navigating Valvular Heart Disease — diagnosis, treatment, caregiving, and the ordinary days in between.
6 stories
Cardiology
Aortic Stenosis Underestimated by Mean Gradient in Atrial Fibrillation
Aortic stenosis (AS) is a common heart valve problem in older adults, and clinicians often judge its severity by
Dr. Abu Bakar · 7 min read
Cardiology
Tricuspid Regurgitation: Simple Clinical Risk Score For Mortality
Tricuspid regurgitation (TR) is a heart valve problem that is often underestimated, but it can seriously affect a
Dr. Abu Bakar · 10 min read
Cardiology
Abbott’s Navitor TAVI System Shows Promising One-Year Results for Aortic Stenosis Care
Abbott’s Navitor transcatheter aortic valve implantation (TAVI) system is drawing new attention after one year outcome data suggested
Dr. Abu Bakar · 8 min read
Cardiology
Tricuspid Regurgitation in Atrial Fibrillation: Incidence, Burden, and Clinical Impact
Tricuspid regurgitation is a condition commonly found in people who have been suffering from atrial fibrillation for quite
Dr. Abu Bakar · 8 min read
Innovation & Devices
Vdyne Granted FDA IDE For Tricuspid Valve Replacement Study
The FDA granted an investigational device exemption (IDE) to Vdyne for their tricuspid valve replacement (TTVR) device allowing
Rayan Salih · 10 min read
Questions clinicians ask
- What does the evidence show about the incidence and clinical impact of tricuspid regurgitation in patients with atrial fibrillation?
- Tricuspid regurgitation appears common among patients with atrial fibrillation and is associated with substantial disease burden and adverse clinical outcomes. The evidence supports its relevance during risk assessment in this population but does not establish atrial fibrillation as its sole cause.
- Can a simple clinical risk score identify patients with tricuspid regurgitation who have a higher mortality risk?
- The available brief describes a simple clinical score that stratifies patients with tricuspid regurgitation according to mortality risk. Its applicability is prognostic, complementing clinical and valve assessment rather than defining a specific treatment strategy.
- Can mean transvalvular gradient underestimate aortic stenosis severity in patients with atrial fibrillation?
- Evidence indicates that mean gradient can underestimate aortic stenosis severity when atrial fibrillation is present. This finding applies to patients with both conditions and highlights the limitations of classifying severity from mean gradient alone.
- What does recent evidence show about intervention options and timing across aortic and tricuspid valve disease?
- One-year findings for the Navitor transcatheter aortic valve implantation system were promising in patients treated for aortic stenosis, although the brief does not establish superiority over other systems. For tricuspid disease, the FDA investigational device exemption permits study of Vdyne's replacement device but does not demonstrate safety or effectiveness. Separate coverage of aortic regurgitation suggests that earlier intervention may improve outcomes, without defining a specific threshold or eligible population.
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